Biological Sciences
BIO 202: Molecular Biology and Developmental Biology (Credit, 3)
Course Contents:
- DNA replication
- Transcription and processing of RNA
- Translation and post-translational processes leading to synthesis of mature proteins
- Protein targeting and sorting,
- RNA replication, reverse transcription
- Regulation of gene expression
- 1. Introduction to Developmental Biology
-Historical perspective of embryology
-Theory of preformation, epigenesis and recapitulation
-Principles of developmental Biology - -Mechanisms of diversification of body forms.
- -Concepts of Heterotopy, Heterochrony, Heterometry and Heterotypy.
- Gamete structure, development and fertilization
- -Cleavage and gastrulation in Xenopus
- -Axis formation of Xenopus
- Spatiotemporal patterns of gene expression.
- Morphogens and gradients.
Molecular Biology: Genetic information and its expression
Developmental Biology: Formation of the organism using the genetic information
2 . Evolutionary Developmental Biology (Evo-Devo)
3. Development from fertilization to germ layer formation
4. Genetic basis of Development
5. Introduction to cell signalling – basic concept
Suggested Books:
- Molecular Cell Biology, 8th Edition. by Harvey Lodish et al.,
- Life: The Science of Biology, Vol. I Ninth Edition by David E. Sadava et al.,
- Biological Science by Scott Freeman et al.,
- James D. Watson, et al., Molecular Biology of the Gene, 7th edition,
- Bruce Alberts et al., Molecular Biology of the cell 6th Edition
- Scott F Gilbert, Developmental Biology
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