Biological Sciences
BIO 301: Advanced Cell Biology (Credit, 4)
Course Contents:
Cell: Prokaryotic and Eukaryotic, Structure and organization
Cellular components: Nucleus, Cytoplasm, their structure, organization and function
Organelles: Nucleus, Mitochondria, ER, Golgi, Lysosomes, Chloroplasts Structure, organization and Function
Cell membrane: Synthesis, Components Lipid bilayer/Membrane proteins/Transporters and channels
Solute transport:Membrane and vesicular transport; Compartmentalization and Intracellular transport: Nucleo-cytoplasmic/ER to Golgi/Golgi to Lysosomes/Endocytosis/Exocytosis/
Cytoskeleton: Microtubules, Intermediate filaments, actin filaments and microtubule associated proteins (MAPs);
Molecular motors: components, function
Cell-Cell junctions: Cell-ECM junctions,
Cell signaling: Signaling pathways involving ligands and receptors;
Cell cycle: cell division, cell cycle checkpoint, cell death and apoptosis
Mitosis/Cytokinesis/Meiosis
Apoptotic pathway/Autophagy/Anoikis/Necrosis
Introduction on stem cells/immune cells
Methods to study cell biology: Basics of microscopy, cell surface markers
Suggested Reading:
- Molecular Biology of the Cell (Bruce Alberts).
- Molecular Cell Biology, 8th Edition. (Harvey Lodish).
- The Cell, A Molecular Approach (Geoffrey Cooper).
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