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Indian Institute of Science Education and Research Berhampur

BIO 412: Developmental Biology (4)

Course Content:

History of Embryology and Developmental Biology.
Cell specification, chromosomal theory of inheritance and concept of genome equivalence.
Meiosis, gametogenesis (animals), fertilization and cleavage, morphogen gradients, differentiation, Cell- Cell Communication, cell fate and lineage determination.
Evolutionary Developmental Biology: Modularity, Recruitment and Molecular Parsimony. Developmental constraints on evolution of body forms.
Role of morphogens and their gradient in axis patterning and determination.
Concept of anterior-posterior, dorso-ventral and medio-lateral axis formation;
Development of model organisms like D. melanogaster, C. elegans, X. laevis, G. gallus and M. musculus
Metamorphosis and Regeneration.

Suggested Reading::

• Developmental Biology: Scott F. Gilbert; Sinauer Associates Inc; 2010.
• Essential Developmental Biology: J. Slack; Wiley Blackwell Scientific. 2nd edition; 2005.

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