Dr. Laxmidhar Rout is
an Associate Professor in the Department of Chemical
Sciences at the Indian Institute of Science Education and
Research (IISER) Berhampur, Odisha. He was born in Basudevpur,
Bhadrak, Odisha.
Dr. Rout received his M.Sc. in Chemistry from Utkal University, where he specialized in Synthetic Organic Chemistry under the guidance of Prof. Satyaban Jena. He obtained his Ph.D. in 2008 from the Indian Institute of Technology (IIT) Guwahati under the supervision of Prof. T. Punniyamurthy. After completing his doctoral studies, he pursued postdoctoral research at several internationally renowned institutions. His research focused on organic synthesis, particularly the synthesis of anticancer and antimalarial molecules, asymmetric synthesis, and related areas of medicinal and synthetic chemistry. He worked with Prof. A. M. Harned at the University of Minnesota, USA; Prof. C. G. Zhao at the University of Texas at San Antonio, USA; Prof. S. M. Huber at the Technical University of Munich, Germany; and Dr. Ludger Johannes and Dr. Emmanuel Bassereau at Institut Curie, Paris, France. In recognition of his research excellence, Dr. Rout has been awarded the prestigious Alexander von Humboldt Fellowship (Germany), as well as the FPGG Fellowship and the Institut Curie (IC) Fellowship (France). Before joining IISER Berhampur as an Associate Professor in July 2026, Dr. Rout served as a UGC Assistant Professor at Berhampur University, Odisha, where he accumulated eleven year ten month of teaching and research experience, primarily mentoring postgraduate students and establishing an active research program in synthetic organic chemistry. Dr. Rout has published more than 50 peer-reviewed research articles in leading international journals published by Wiley, Elsevier, the Royal Society of Chemistry (RSC), and the American Chemical Society (ACS). He has also authored eight problem-solving books in Organic Chemistry for BS-MS students, which serve as valuable learning resources for undergraduate and postgraduate education. His current research interests include Synthetic Organic Chemistry, Sustainable Organic Synthesis, Nano-catalysis in Organic Synthesis, Medicinal chemistry, and the development of biologically active molecules. He maintains active research collaborations with scientists from leading academic institutions in India and across the world, contributing to innovative and interdisciplinary research in chemical sciences.
Profile on Researcher's Network
Vidwan
Profile Orchid
Profile Scopous
Pubfact
Google
Scholar Web of Science
Researcher For Details click : Laxmidhar Rout - ldrouts
2026:
Trace Palladium and Copper as Hidden Catalysts in Cross-Coupling Reactions: Roles and Analytical Detection. P. Behera, S. K.Sahu, P. K. Behera, L. Rout, Catal. Sci. Technol. (2026) 16, 3990–4018.
CuNiO₂ Nano Catalyst for Efficient Csp²-S Bond Formation in Water: Toward Green Synthesis of Bioactive Molecules, A. Swain, B. Behera, S. L Samal, L. Rout, Catal. Sci. Technol., (2026),16, 830-839.
2025:
Recent Advances in Transition-Metal-Catalyzed Csp2-X (X = S, N, O) Cross-Coupling Reactions in Water; A. Swain, A. Ouali, E. Soddu, Y. Wang, S. Kar, P. K. Maharana, M. Taillefer, L. Rout* T. Punniyamurthy ;Chem. An Asian, J. (2025), e70471.
Room Temperature Csp2–N Bond Formation Using Pd, Cu and Ni-Catalysts, P. Behera and L. Rout , E. J. Org. Chem. (2025), 28, e202500913
Practical Synthesis of Thio-Cotarnine Analogues; Pradyota K. Behera, Amit K. Pradhan and L. Rout, New J. Chem., (2025),49, 4119-4123
CuMoO4: A Heterogeneous Bimetallic Nanocatalyst for the C-H activation of Alkenes with Iodoarenes P. Behera and L. Rout New J. Chem., (2025),49, 18692-18697
2024:
Recent advances in transition-metal-catalyzed (Csp2)-X (X = Se, Te, As, Sb) bond formation; L. Rout, Papita Behera and T. Punniyamurthy, Molecular Catalysis, (2024), 557, 113993;
CuMoO4 nano catalyst for Csp2-O cross-couplings; Easy access to nitrofen derivatives; P. K.. Behera, P. Behera, A. Swain, S. K. Sahu, A. Sahoo and L. Rout, New J. Chem., (2024),48, 687-692
2023:
Immunomodulatory and anti-inflammatory and anticancer activities of porphyran, a sulfated galactan, B. Pradhan, J.-S. Ki and L. Rout, Carbohydrate Polymers, (2023), 301, Part A, 120326
2022:
CuMoO4 Catalyzed Csp 2-Se Cross-Coupling of Aryl Bromide and Iodide with Diaryldiselenides in Water; P Choudhury, A. K. Pradhan, S. Jena, B. K. Sahoo, S. K. Sahu, P. K. Behera, P. Behera, A. Swain, and L. Rout ,Eur. J. Org. Chem (2022) 2022, 48, e202201194
MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer; D. P. Panigrahi, S. Patra, B. P. Behera, P. K. Behera, S. Patil, B.S. Patro, L. Rout, ,I. Sarangi , S. K. Bhutia, Free Radical Biology and Medicine, (2022), 2022, 190, 307.
Efficient Oxygen Bridged Bimetallic CuSeO3.2H2O Catalyzed (CSP2-CSp) Sonogasira Cross-Coupling of Terminal Aryl Acetylene with Haloarenes, S. K. Sahu, P. Choudhury, and. L. Rout et al, New. J. Chem, (2022) 46, 1650-1657.
2021:
Recent advance in [3+2] cycloa ddition of allene with 1,3-carbonyl ylide; Rh(II) catalyzed access to bridged polyoxocarbocyles; S. K. Sahu, and L. Rout et al New. J. Chem, (2021) 45, 11018-11029
Oxygen bridged bimetallic CuMoO4nanocatalyst; [Cu-O-Mo] for dehydrogenative benzylic alcohol oxidation and DFT study P.K. Behera, and Prof. L. Rout et al; A. J. Org. Chem. (2021) 10, 1117-1122
Efficient oxygen bridged bimetallic CuSeO3.2H2O catalyzed dehydrogenative oxidation of benzylic alcohol. P. Choudhury, and Prof. L. Rout et al New. J. Chem, (2021), 45, 5775-5779
Recent Advances in Transition-Metal-Mediated Csp2-B and Csp2-P Cross-Coupling Reactions, L. Rout, T. Punniyamurthy, Coord. Chem. Rev., (2021), 431, 213675,
Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics, S. Patra; B. Pradhan; R. Nayak; C. Behera; L. Rout, M. Jena, T. Efferth, S. K. Bhutia, Seminars in Cancer Biology, (2021), 73, 310-320
2020:
Developments in chemistry and biological application of cotarnine & its analogs ” S. K. Sahu, P.K. Behera, P. Choudhury, S.Panda, L. Rout, Tetrahedron (2020), 76,50, 131663
Bimetallic BaMoO4 Nanoparticle for C-S Cross-Coupling of Thiols with Haloarene, S. Panda, R.; Panigrahi, P. Behera, S. Sahu, L. Rout, New J. Chemistry, (2020), 44, 2500-2504.
CuMoO4 Bimetallic Nanoparticles, An Efficient Catalyst for Room Temperature C-S Cross-coupling of Thiols and Haloarenes; R. Panigrahi, S. Panda, P. Behera, S. Sahu, L. Rout, Chem.- Eur. J, (2020), 26, 620
Recyclable Bimetallic CuMoO4 Nanoparticle for C-N Cross-Coupling Reaction Under Mild Condition, R. Panigrahi, S. Panda, P. Behera, S. Sahu, L. Rout, New J. Chemistry, (2019) 43, 19274
2018:
Synthesis of of acyl derivatives of cotarnine L. Rout, B. Emmanuel, A. K. Sahoo Org. Synth, (2018), 95, 455
2017:
Metal Free Activation of C(SP3)-H Bond, Practical and Rapid Synthesis of Privileged 1-Substituted-1,2,3,4-Tetrahydroisoquinolines, L. Rout, , J.-C. Florent, L. Johannes, S. K. Choudhury, P. Rout, E. Bertounesque, Eur J. Org. Chem (2017), 35, 5275-5292
2016:
Metal-Free Activation of a C(sp)−H Bond of Aryl Acetylenes, L. Rout,. J.-C. Florent, L. Johannes, S. K. Choudhury, J. Scanlon, E. Bertounesque, Chem. - Eur. J. (2016), 22,14812–14815.
2014:
Activation of a Carbonyl Compound by Halogen Bonding S. H. Jungbauer, F. Kniep, S.M. Walter, S. Schinder, L. Rout, S. M. Huber; Chem. Cumm, (2014), 50, 6281
2012:
5-Iodo-1,2,3-triazolium-based multidentate halogen-bond donors as activating reagents, F. Kniep, L. Rout, S.M. Walter, H. K. V. Bensch, S. H. Jungbauer, E. Herdtweck, S. M. Huber Chem. Comm, (2012), 48, 9299.
Synthesis of Isothermal Calorimetric Titrations on Charge-Assisted Halogen Bonds: Role of Entropy, Counter ions, Solvent, and Temperature S. M. Walter, F. Kniep, L. Rout, F. P. Schmidtchen, E. Herdtweck, S. M. Huber, J. Am. Chem. Soc. (2012), 134, 8507.
2011:
Synthesis of -Arylphosphonates Using Copper-Catalyzed -Arylation and Deacylative -Arylation of -Ketophosphonates. L. Rout, S. Regati and C. G. Zhao, Adv. Synth. Catal. (2011), 353, 3340.
Organocatalytic Highly Enantioselective Synthesis of -Formyl-hydroxyphosphonates; S. Perera, V. K. Naganaboina, L.Wang, B. Zhang, Q. Guo, L. Rout, C.-G. Zhao; Adv. Synth. Catal. (2011), 353, 1729.
2010:
Axial Chiral Allenes as Dipolarphiles in Rh-Catalyzed Carbonyl Ylide Cycloaddition. L. Rout and A. M. Harned., Chem. Eur. J. (2010),15, 12926.
2009:
CuO Nanoparticles Catalyzed C−N, C−O, and C−S Cross-Coupling Reactions: Scope and Mechanism S. Jammi, L. Rout, S. Sakthivel, T. Mukherjee, S. Mandal, R. Mitra, P. Saha, T. Punniyamurthy J. Org. Chem. (2009), 74, 1971.
Synthesis, Structure, and Application of Self-Assembled Copper(II) Aqua Complex by H-Bonding for Acceleration of the Nitroaldol Reaction in Water S. Jammi, Md A. Ali, S. Sakthivel, L. Rout, T. Punniyamurthy, Chem. Asian. J. (2009),4, 314-320.
2008:
Synthesis, Crystal Structure and Application of Chiral Copper(II) Polymers for Asymmetric Acylation of Secondary Alcohols. S. Jammi, L. Rout, P. Saha, V. K. Akhilagunta, S. Sanyasi and T. Punniyamurthy, Inorg. Chem. (2008), 12, 5093,
Efficient Ligand-Free Nickel-Catalyzed C-S Cross-Coupling of Thiols with Aryl Iodides. S. Jammi, P. Barua, L. Rout, P. Saha, T. Punniyamurthy, Tetrahedron. Lett. (2008), 49,1484.
Efficient Copper(I) Catalyzed C-S Cross-Coupling of Thiols with Aryl Halides in Water; L. Rout, P. Saha, T. Punniyamurthy, Eur. J. Org. Chem. (2008), 4, 640-643.
Recent Advances in Copper-Catalyzed Oxidation of Organic Compounds. T. Punniyamurthy , L. Rout, Coord. Chem. Rev. (2008), 252, 134.
Cadmium(II) Catalyzed C-N Cross-Coupling of Amines with Aryl Iodides. L. Rout, S. Jammi,T. Punniyamurthy, Adv. Synth. Catal. (2008), 350, 395.
Efficient CuO Nanoparticle Catalyzed C-S Cross Coupling of Thiols with Iodobenzene; L. Rout, T. K. Sen and T. Punniyamurthy, Angew. Chem. Int. Ed. Eng (2007), 46, 5583.
2007:
Novel CuO Nanoparticle Catalyzed C-N Cross-Coupling of Amines with Iodobenzene.; L. Rout, S. Jammi, T. Punniyamurthy, Org. Lett. (2007), 9, 3397.
Chiral Linear Polymers Bonded Alternatively with Salen and 1,4-Dialkoxy-2,6-diethynylbenzene: Synthesis and Application to Diethylzinc Addition to Aldehydes. S. Jammi, L. Rout and T. Punniyamurthy, Tetrahedron: Asymmetry (2007),17,2016.
Vanadium-Catalyzed Selective Oxidation of Alcohols to Aldehydes and Ketones with t-BuO2H L. Rout and T. Punniyamurthy, Adv. Synth. Catal. (2007), 349, 846
Silica-Supported Vanadium-Catalyzed N-Oxidation of Tertiary Amines with Aq. H2O2. L. Rout and T. Punniyamurthy, Adv. Synth. Catal. (2005), 347, 1958
1. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Name reaction, Rearrangements and Mechanism; Problem Solving Approach, 2024; ISBN NO: 978-81-19907-53-3, Indu Book Service Private Limited, New Delhi -110002
2. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Pericyclic and Photochemistry; Problem Solving Approach, 2024; ISBN NO: 978-81-19907-91-5; Indu Book Service Private Limited, New Delhi -110002
3. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Advanced Organic Spectroscopy ; Problem Solving Approach, 2024, ISBN NO: 978-81-19907-76-2, Indu Book Service Private Limited, New Delhi -110002
4. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Reagent and Mechanism in Organic Synthesis; Problem Solving Approach, 2024; ISBN NO: 978-81-19907-48-9; Indu Book Service Private Limited, New Delhi -110002
5. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Retrosynthesis and application; Problem Solving Approach, 2024; ISBN NO: 978-93-91-377-78-6; Indu Book Service Private Limited, New Delhi -110002.
6. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Stereochemistry, Conformations and Asymmetric Synthesis ; Problem Solving Approach, 2024 ISBN NO: 978-81-19907-67-0, ISBN NO: 978-81-19907-67-0, Indu Book Service Private Limited, New Delhi -110002.
7. Prof. Satyaban Jena and Dr. Laxmidhar Rout, General Organic Chemistry ; Problem Solving Approach, 2024. ISBN NO: 978-81-19907-72-4, Indu Book Service Private Limited, New Delhi -110002
8. Prof. Satyaban Jena and Dr. Laxmidhar Rout, Advanced Heterocyclic Chemistry ; Problem Solving Approach, 2024. ISBN NO: 978-81-19907-98-4, Indu Book Service Private Limited, New Delhi -110002
Book Chapter:
P. Behera and L. Rout, Chapter 10014 Vinyl and Aryl Chalcogenides: Sulfur-, Selenium-, and Tellurium-based Functional Groups, Comprehensive Organic Functional Group Transformations III, ISBN 0080406041, 9780080406046 2026
· 1: DOS Approach for Synthesis of Sesquiterpene Anti-malaria Drugs: 2017-2020; (SERB/EMR/2016/006898) SERB New Delhi, India, 8.06 lakh (Completed).
· 2: Synthetic Utility of Axial Chiral Allenes and Application in Natural Product Synthesis 2017-19, UGC-Start-UP-Grant-F-45(58)/2014, (BSR/FRP),UGC New Delhi, 6.00 lakh (Completed).
· 3: Diversified Chiral Hemicotarnines. for Future Cancer Drug 2018-2021, 27562800512017 /20 /1370 / S&T, S & T, Govt. of Odisha, 8.16 lakh (Completed).
· 4:Copper based bimetallic heterogeneous
nano-catalyst for cross-coupling reaction 2021-24,
CSIR/02(0393)/21/EMR-II, 01/04/2021-23, CSIR New Delhi, 27.14 Lakh
· 5: Hiyama cross-coupling of unactivated
electrophiles and silanes using new catalytic system, CRG/2022/001544, SERB New
Delhi India, 45. 67 lakh
· 6:DOS Approach for Sulfur Based
Tetrahydroisoquinoline Anti-Cancer Drugs” 2023-2026, S&T S
& T, Govt. of Odisha, 10.00
lakh
· 7: Sustainable Catalyst for Carbon-Carbon Cross-coupling Reactions, MRI, 284/249/ OSHEC, OSHEC, MRIP Odisha, 8,52 lakh (Completed).
