Dr. Barla Thirupathi was born in Madavelli, Telangana, in 1984. He completed his M.Sc. in Organic Chemistry at Osmania University (2006–2008) and subsequently worked at Aragen Life Sciences before joining CSIR–IICT, Hyderabad, as a Junior Research Fellow for his Ph.D. under the supervision of Dr. D. K. Mohapatra (2009–2015). He later served as an Associate Research Scientist at Sai Life Sciences.
From 2015 to 2018, he pursued postdoctoral research at Harvard University with Prof. E. J. Corey, where he developed fluorinated second-generation oxazaborolidine catalysts for enantioselective Diels–Alder reactions. In 2018, Dr. Thirupathi joined IISER Berhampur as an Assistant Professor of Chemistry and was promoted to Associate Professor in February 2024.
He is a recipient of the 2023 Thieme Chemistry Journals Award, a Life Member of the Chemical Research Society of India (CRSI), and an Associate Fellow of the Telangana Academy of Sciences (2024).
36. Ynones as Versatile Electrophiles for the DivergentSynthesis of 4H-Chromenes and 1,4-Dihydroquinolines, Mishra, G.; Potnuru, I.;Muduli, G.; Thirupathi B*. Organic & Biomolecular Chemistry, 2026, Acceptedarticle, (doi: 10.1039/D6OB00097E).
35. Synthesis of Spiro[indane-1,3-dione-2-pyrrolidines] by theReaction of 2-(2′-Ketoalkyl)-1,3-Indandiones with Triazinanes, Pal, B. K.;Sahoo, S.; Mondal S., Thirupathi, B.* Journal of Organic Chemistry, 2026, 91, 3239–3245.
34. CollectiveTotal Synthesis of (+)- and (−)-Baoslingzhines F–H, (+)- and (−)-Chizhiene C,and (+)- and (−)-Lingzhines E and F, Patra, N.; Akshaya, S.; Goshwami, S.;Sanker, H.; D., Ruthrotha S. B., Thirupathi, B.* Organic Letters, 2026, 28, 1090–1094
33. Mishra, G.; Bobonga, M. S.; Islam, K.; Thirupathi, B.; DABCO-catalysed highly diastereoselective synthesis of 1,3-indandione containing fully saturated spirocyclopentanes involving 2-(2′-ketoalkyl)-1,3-indandiones and nitrostyrenes, RSC Advances, 2025, 15, 30768-30780.
https://pubs.rsc.org/en/content/articlelanding/2025/ra/d5ra04224k
32. Mandal, S.; Kundu, S.; Thirupathi, B.* Total Synthesis, Determination of Absolute Configuration, Antibacterial Efficacy of Colletotrichumolide, and Its 3R-Diastereomer, Journal of Organic Chemistry, 2025, 90, 7902–7909.
https://pubs.acs.org/doi/10.1021/acs.joc.5c00832
31. Kundu, S.; Mandal, S.; Thirupathi, B.* Kobayashi’s Aryne Precursor for the One-Step Synthesis of Anthraquinones and Its Application to the Total Synthesis of Chrysophanol, Danthron, and Physcion, Journal of Organic Chemistry, 2025, 90, 2472–2478.
https://pubs.acs.org/doi/10.1021/acs.joc.4c03041
30. Mishra, G.; Indu, P.; Sasmal, M.; Thirupathi, B.* Synthesis of Sulfone Containing-Spirocycles, -Pentafulvene Dyes and Their Photophysical Properties (Invited article), European Journal of Organic Chemistry, 2025, e202401311
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.202401311
29. Pal, B. K.; Sahoo, K.; Sourav D., Ruthrotha S. B., Thirupathi, B.* Rapid Assembly of 1,3-Dicarbonyl Fused 5-phenyl-1-Azabicyclo[3.1.0]hexanes and Their Cytotoxic Activities, Organic Letters, 2025, 27, 761-766.
https://pubs.acs.org/doi/10.1021/acs.orglett.4c04394
28. Mishra, G.; C. M, Y., Thirupathi, B*. Synthesis of Spirocyclic-1,3-indandione Containing-Cyclopentenones and -Benzotropones, Chemistry An Asian Journal, 2024, e202400667.
https://aces.onlinelibrary.wiley.com/doi/10.1002/asia.202400667
27. Sahoo, K.; Patra, N.; Dandela, R.; Thirupathi, B*. A Three-Component Synthesis of Spiropyrrolines. Journal of Organic Chemistry 2024, 89, 5337-5352.
https://pubs.acs.org/doi/full/10.1021/acs.joc.3c02713
26. Mandal, S.; Mahananda, D.; Paladugu, D.; Thirupathi, B*. Total Synthesis and Determination of the Absolute Configuration of Berkeleylactone I. Journal of Organic Chemistry 2024, 89, 4165-4175.
https://pubs.acs.org/doi/10.1021/acs.joc.4c00178
25. Mandal, S.; Mahananda, D.; Dey, S.; Bharathavikru, R. S.; Thirupathi, B*. Total Synthesis, Revised Structure, and Biological Evaluation of Elgonene B and Analogues. Journal of Natural Products 2024, 87, 152-159.
https://pubs.acs.org/doi/10.1021/acs.jnatprod.3c00988
25. Synform Interview of Barla Thirupathi as a Young Career Focus Presentation: DOI: 10.1055/s-0040-1720624 Synform 2024/03, A41–A43
23. Mishra, G.; Sasmal, M.; Chakraborty, A.; Thirupathi, B*. Synthesis of Highly Functionalized Spirocycles and Pentafulvene-Containing Dyes Involving 2-(2′-ketoalkyl)-1,3-indandiones. Chemistry - A European Journal 2023, 29, e202301976.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202301976
22. Hazra, G.; Kundu, S.; Dandela, R.; Thirupathi, B*. Cascade Nucleophilic Addition-Cyclic Michael Addition of Arynes and Indoles Bearing Michael Acceptor: A Strategy to Construct Pyrroloacridines and Study of Their Physicochemical Properties. Journal of Organic Chemistry 2023, 88, 8493-8504.
https://pubs.acs.org/doi/10.1021/acs.joc.3c00462
21. Hazra, G.; Dinesh, S.; Sahoo, K.; Thirupathi, B*. Recent advances with cobalt-mediated asymmetric hydrogenations. Results in Chemistry 2023, 5, Review. DOI: 10.1016/j.rechem.2023.100843
https://www.sciencedirect.com/science/article/pii/S2211715623000826?via%3Dihub
20. Pothireddy, M.; Hazra, G.; Babu, P. V.; Thirupathi, B*.; Dandela, R. Synthesis of Fluorinated 2-Benzylphthalazin-1(2 H)-one, 1-Phthalazinamine, and 1-Alkoxy/Benzyloxyphthalazine Derivatives by an Ultrasonication Method. Synlett 2022, 33, 1716-1722, Article. DOI: 10.1055/a-1846-5200
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1846-5200
19. Pothireddy, M.; Bhukta, S.; Babu, P. V.; Thirupathi, B*.; Dandela, R. Synthetic method to access fluorinated 2-benzylpyridines by using Negishi coupling reaction. Synthetic Communications 2022, 52, 564-576,
https://www.tandfonline.com/doi/full/10.1080/00397911.2022.2037651
18. Mandal, S.; Thirupathi, B*. Total synthesis of proposed elgonene C and its (4R,5R)-diastereomer. Organic and Biomolecular Chemistry 2022, Article. DOI: 10.1039/d2ob00094f
https://pubs.rsc.org/en/content/articlelanding/2022/ob/d2ob00094f
17. Hazra, G.; Mishra, G.; Dandela, R.; Thirupathi, B*. A Method to Access Highly Functionalized Dibenzobicyclo[3.2.1]octadienones: Application to the Construction of the 6/6/5/6/6 Carbon Skeleton of Rubialatin A. Journal of Organic Chemistry 2022, 87, 11925-11938.
https://pubs.acs.org/doi/10.1021/acs.joc.2c00340
16. Thirupathi, B*.; Jena, B. K. Total Synthesis of (+)-Sacrolide A. ChemistrySelect 2019, 4, 2908-2911.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201900192
15. Mandal, S.; Thirupathi, B*. Strategies for the construction of γ-spirocyclic butenolides in natural product synthesis. Organic and Biomolecular Chemistry 2020, 18, 5287-5314.
https://pubs.rsc.org/en/content/articlelanding/2020/ob/d0ob00954g
14. Thirupathi, B*.; Zilla, M. K. Syntheses and Biological Importance of Herboxidiene/GEX1A. ChemistrySelect 2019, 4, 11944-11958.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201902742
13. Thirupathi, B*.; Jena, B. K. Total Synthesis of (+)-Sacrolide A. ChemistrySelect 2019, 4, 2908-2911.
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.201900192
(Top downloaded article among work published between January 2018 and December 2019 in its journal)
